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Re: iwfal post# 171853

Saturday, 01/12/2019 12:46:33 PM

Saturday, January 12, 2019 12:46:33 PM

Post# of 423928

You may not like it, but there was a substantial fraction of the cardio MD community that was extremely doubtful (presumably bc of the long history of failure).



"Substantial fraction"? How do you know that? Herpes found 4-5 docs who claimed the placebo harmed patients or questioned whether the results were valid - I seriously doubt they are in the majority.


Prediction: it will happen again when they get the first positive Ph3 for one of the drugs that lowers stroke clotting wo increasing bleeds. It’s opportunity.



Is that even physically possible? I'm no expert on blood clotting, but on the surface it seems to me such a drug could not be created. Well, wait a second - we sorta already have one of those, don't we? V lowered risk of stroke by 30% and patients did not have increased/worrisome bleeding problems. I realize semantically low risk of stroke is not equivalent to "lower stroke clotting", but the end game is preventing strokes, so isn't that what really matters?

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