Friday, December 28, 2018 4:30:51 PM
OFP, Thanks For Pointing Out The Error — Corrected
Here are the base metrics:
5,700,000 Americans have Alzheimer’s.
https://alz.org/media/Documents/alzheimers-facts-and-figures-infographic.pdf
Approximately 44 million people worldwide living have Alzheimer’s disease or a related dementia.
https://alzheimersnewstoday.com/alzheimers-disease-statistics/
An estimated seven to 10 million people worldwide are living with Parkinson’s disease.
Approximately 60,000 Americans are diagnosed with Parkinson’s disease each year,....
http://www.parkinsonassociation.org/facts-about-parkinsons-disease/
...a global study of the impact of a wide range of health conditions published in 2017, estimated that just over 6 million people across the world are currently living with Parkinson’s.
https://medium.com/parkinsons-uk/how-many-people-have-parkinsons-61d04979a770
So, for these two diseases, across the world, there are about 50 million potential Anavex patients — with far greater numbers as world populations emerge into old age.
Ok, let’s assume that Anavex will be used to treat only 5% of the global populations of these two diseases. That’s a patient population of 2.5 million.
Big unknown here. How much will each patient (or her government or health insurance company) pay for a year of Anavex treatment? How much will Anavex charge? We can only guestimate.
At $5 a day, that’s an annual per-patient revenue gain by Anavex Life Sciences Corp about $1800. At $10 a day, about $3600.
To find gross annual corporate revenues, multiply those per-patient revenue numbers times the number of patients treated. Lots of zeros.
Estimating drop-downs (if there will be any) for dividends is very hazy. If dividends are 10% of gross corporate revenues, multiply them times 0.1. For per-share dividends, divide that metric by the number of outstanding shares (presently ~46.5 million).
Then, presume some price/earnings ratio, and multiple the dividend price by that datum. That gives an estimate of the share price. PE ratios are commonly (now), as far as I can tell, from 1/10 to 1/25. (I’m a biologist, not an astute student of stock investment details — correct me on any of this, please.)
Of course, all of these metrics are hazy; can vary widely. Punching the numbers will require high-range and low-range lines for each.
Nonetheless, even at the lowest range, say, Anavex treating only 2.5 million people a year, at an annual pills cost of $5/day ($1800 per year), this yields gross annual corporate revenues of $4,500,000,000. That’s $4.5 billion.
But maybe therapeutic doses will cost only $0.50 per day (not $5.) With that, annual per-patient revenues would be about $180. With 2.5 million patients per year, corporate revenues would be only $450,000,000; four and half million dollars.
Of course, if Anavex never gets a drug to market (the clinical trials all fail), all of the revenue numbers will be zero. Don’t invest dollars in AVXL you can’t afford to lose. Informed speculation, best only with discretionary dollars — all dependent upon successful clinical trials results (which appear from extensive murine studies to be very likely).
(Now, was that “pumping?”)
Here are the base metrics:
5,700,000 Americans have Alzheimer’s.
https://alz.org/media/Documents/alzheimers-facts-and-figures-infographic.pdf
Approximately 44 million people worldwide living have Alzheimer’s disease or a related dementia.
https://alzheimersnewstoday.com/alzheimers-disease-statistics/
An estimated seven to 10 million people worldwide are living with Parkinson’s disease.
Approximately 60,000 Americans are diagnosed with Parkinson’s disease each year,....
http://www.parkinsonassociation.org/facts-about-parkinsons-disease/
...a global study of the impact of a wide range of health conditions published in 2017, estimated that just over 6 million people across the world are currently living with Parkinson’s.
https://medium.com/parkinsons-uk/how-many-people-have-parkinsons-61d04979a770
So, for these two diseases, across the world, there are about 50 million potential Anavex patients — with far greater numbers as world populations emerge into old age.
Ok, let’s assume that Anavex will be used to treat only 5% of the global populations of these two diseases. That’s a patient population of 2.5 million.
Big unknown here. How much will each patient (or her government or health insurance company) pay for a year of Anavex treatment? How much will Anavex charge? We can only guestimate.
At $5 a day, that’s an annual per-patient revenue gain by Anavex Life Sciences Corp about $1800. At $10 a day, about $3600.
To find gross annual corporate revenues, multiply those per-patient revenue numbers times the number of patients treated. Lots of zeros.
Estimating drop-downs (if there will be any) for dividends is very hazy. If dividends are 10% of gross corporate revenues, multiply them times 0.1. For per-share dividends, divide that metric by the number of outstanding shares (presently ~46.5 million).
Then, presume some price/earnings ratio, and multiple the dividend price by that datum. That gives an estimate of the share price. PE ratios are commonly (now), as far as I can tell, from 1/10 to 1/25. (I’m a biologist, not an astute student of stock investment details — correct me on any of this, please.)
Of course, all of these metrics are hazy; can vary widely. Punching the numbers will require high-range and low-range lines for each.
Nonetheless, even at the lowest range, say, Anavex treating only 2.5 million people a year, at an annual pills cost of $5/day ($1800 per year), this yields gross annual corporate revenues of $4,500,000,000. That’s $4.5 billion.
But maybe therapeutic doses will cost only $0.50 per day (not $5.) With that, annual per-patient revenues would be about $180. With 2.5 million patients per year, corporate revenues would be only $450,000,000; four and half million dollars.
Of course, if Anavex never gets a drug to market (the clinical trials all fail), all of the revenue numbers will be zero. Don’t invest dollars in AVXL you can’t afford to lose. Informed speculation, best only with discretionary dollars — all dependent upon successful clinical trials results (which appear from extensive murine studies to be very likely).
(Now, was that “pumping?”)
Recent AVXL News
- Anavex Life Sciences Highlights New Scientific Findings on Shared Biology Between Autism and Alzheimer’s Disease • GlobeNewswire Inc. • 04/14/2026 11:30:00 AM
- Anavex Life Sciences to Present at the 25th Annual Needham Virtual Healthcare Conference • GlobeNewswire Inc. • 04/07/2026 11:30:00 AM
- Anavex withdraws EU approval filing for Alzheimer’s therapy • IH Market News • 03/30/2026 12:39:26 PM
- Anavex Life Sciences Provides Comprehensive Regulatory Update • GlobeNewswire Inc. • 03/30/2026 11:30:00 AM
- Form 8-K - Current report • Edgar (US Regulatory) • 03/25/2026 08:06:00 PM
- Anavex withdraws EU marketing application for Alzheimer’s therapy blarcamesine • IH Market News • 03/25/2026 02:06:58 PM
- Anavex Life Sciences Provides Update on Regulatory Review in the EU for Blarcamesine to Treat Early Alzheimer’s Disease • GlobeNewswire Inc. • 03/25/2026 11:30:00 AM
- Anavex Life Sciences Presents New Data from its AD-004 Phase IIb/III Trial at AD/PD 2026 Conference Demonstrating Consistent Correlation Between the Treatment Effect of Oral Blarcamesine and Preservation of Brain Volume in Early Alzheimer’s Disease • GlobeNewswire Inc. • 03/23/2026 11:30:00 AM
- New Scientific Findings Highlight Hypothesis of Autophagy Failure as a Precursor of Amyloid Beta and Tau Pathology in Alzheimer’s Disease • GlobeNewswire Inc. • 03/20/2026 11:30:00 AM
- Anavex Life Sciences Presents Significant Treatment Effects of Blarcamesine in New Advanced Alpha-Synuclein Model of Parkinson’s Disease at AD/PD 2026 Conference • GlobeNewswire Inc. • 03/17/2026 11:30:00 AM
- Anavex Life Sciences to Present at the Citizens Life Sciences Conference • GlobeNewswire Inc. • 03/03/2026 12:30:00 PM
- Anavex Life Sciences to Present at the 46th TD Cowen Annual Health Care Conference • GlobeNewswire Inc. • 02/25/2026 12:30:00 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 02/25/2026 11:07:01 AM
- Anavex Life Sciences Appoints Seasoned Healthcare Leader to Board of Directors • GlobeNewswire Inc. • 02/23/2026 12:30:00 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 02/09/2026 09:40:27 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 02/09/2026 12:31:17 PM
- Anavex Life Sciences Reports Fiscal 2026 First Quarter Financial Results and Provides Business Update • GlobeNewswire Inc. • 02/09/2026 12:30:00 PM
- Anavex Life Sciences to Announce Fiscal 2026 First Quarter Financial Results on Monday, February 9, 2026 • GlobeNewswire Inc. • 02/03/2026 12:30:00 PM
- Anavex Joins ACCESS-AD, a Major Initiative Funded by the European Commission, Through the Clinical Evaluation of Blarcamesine as Part of a Precision Medicine Approach in Alzheimer’s Disease • GlobeNewswire Inc. • 01/13/2026 12:30:00 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 01/09/2026 10:26:26 PM
- Edelson Lechtzin LLP Announces an Investigation of Anavex Life Sciences Corp. (NASDAQ: AVXL) and Encourages Investors with Substantial Losses Contact the Firm • PR Newswire (US) • 01/09/2026 01:13:00 AM
- Anavex Life Sciences Appoints Senior Vice President Global Head of Neurology • GlobeNewswire Inc. • 01/08/2026 12:30:00 PM
- Anavex Life Sciences Receives FDA Feedback on Alzheimer’s Disease Program • GlobeNewswire Inc. • 01/06/2026 12:30:00 PM
- Anavex Life Sciences Submitted Request for EMA to Re-Examine Its Opinion • GlobeNewswire Inc. • 12/18/2025 12:30:00 PM
- Anavex Life Sciences Provides Update on Regulatory Review in the EU for Blarcamesine to Treat Early Alzheimer’s Disease • GlobeNewswire Inc. • 12/12/2025 09:05:00 PM
