Friday, December 21, 2018 3:37:35 PM
Anavex Results in Murines and Humans Are Unique
What’s unique about Anavex 2-73? Simple. In both murines (numerous published studies) and in human applications (preliminary, small-n Australian study), the molecule has shown a) safety and b) efficacy against various CNS diseases. Tell us, if you will, an existing drug that matches or exceeds murine results with Rett, Parkinson’s, or Alzheimer’s (not just Alzheimer's).
Of course, none of that is sufficient for regulatory approval of the drug yet. Murines aren’t humans. You, as you have, will contend that no studies, murine or human, show efficacies. That’s your contention; just fine. You are welcome to that perspective. Often stated.
Of course, nothing to date, pro or con, is altogether valid. Only legitimate results of any of the three late-phase clinical trials are important. For investors with your perspective, evidence is insufficient to support an AVXL equity purchase. But for others, the record of safety, tolerability, and efficacy of Anavex 2-73, in both murines and humans, is sufficient for many of us to take small, speculative but informed AVXL positions.
Let’s check back in December 2019 and see if Anavex 2-73 has proven to be “unique” in any way in the treatment of Rett syndrome girls, and people with Parkinson’s and Alzheimer’s. Then, nothing will be conjectural or without evidence.
A unique perspective, for a unique drug, perhaps?
In light of the above, please point to any aspect of your post you still feel is unique...I don't believe there is anything.
Of course, none of that is sufficient for regulatory approval of the drug yet. Murines aren’t humans. You, as you have, will contend that no studies, murine or human, show efficacies. That’s your contention; just fine. You are welcome to that perspective. Often stated.
Of course, nothing to date, pro or con, is altogether valid. Only legitimate results of any of the three late-phase clinical trials are important. For investors with your perspective, evidence is insufficient to support an AVXL equity purchase. But for others, the record of safety, tolerability, and efficacy of Anavex 2-73, in both murines and humans, is sufficient for many of us to take small, speculative but informed AVXL positions.
Let’s check back in December 2019 and see if Anavex 2-73 has proven to be “unique” in any way in the treatment of Rett syndrome girls, and people with Parkinson’s and Alzheimer’s. Then, nothing will be conjectural or without evidence.
A unique perspective, for a unique drug, perhaps?
Recent AVXL News
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- Anavex Life Sciences to Present at the 25th Annual Needham Virtual Healthcare Conference • GlobeNewswire Inc. • 04/07/2026 11:30:00 AM
- Anavex withdraws EU approval filing for Alzheimer’s therapy • IH Market News • 03/30/2026 12:39:26 PM
- Anavex Life Sciences Provides Comprehensive Regulatory Update • GlobeNewswire Inc. • 03/30/2026 11:30:00 AM
- Form 8-K - Current report • Edgar (US Regulatory) • 03/25/2026 08:06:00 PM
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- Anavex Life Sciences Presents New Data from its AD-004 Phase IIb/III Trial at AD/PD 2026 Conference Demonstrating Consistent Correlation Between the Treatment Effect of Oral Blarcamesine and Preservation of Brain Volume in Early Alzheimer’s Disease • GlobeNewswire Inc. • 03/23/2026 11:30:00 AM
- New Scientific Findings Highlight Hypothesis of Autophagy Failure as a Precursor of Amyloid Beta and Tau Pathology in Alzheimer’s Disease • GlobeNewswire Inc. • 03/20/2026 11:30:00 AM
- Anavex Life Sciences Presents Significant Treatment Effects of Blarcamesine in New Advanced Alpha-Synuclein Model of Parkinson’s Disease at AD/PD 2026 Conference • GlobeNewswire Inc. • 03/17/2026 11:30:00 AM
- Anavex Life Sciences to Present at the Citizens Life Sciences Conference • GlobeNewswire Inc. • 03/03/2026 12:30:00 PM
- Anavex Life Sciences to Present at the 46th TD Cowen Annual Health Care Conference • GlobeNewswire Inc. • 02/25/2026 12:30:00 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 02/25/2026 11:07:01 AM
- Anavex Life Sciences Appoints Seasoned Healthcare Leader to Board of Directors • GlobeNewswire Inc. • 02/23/2026 12:30:00 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 02/09/2026 09:40:27 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 02/09/2026 12:31:17 PM
- Anavex Life Sciences Reports Fiscal 2026 First Quarter Financial Results and Provides Business Update • GlobeNewswire Inc. • 02/09/2026 12:30:00 PM
- Anavex Life Sciences to Announce Fiscal 2026 First Quarter Financial Results on Monday, February 9, 2026 • GlobeNewswire Inc. • 02/03/2026 12:30:00 PM
- Anavex Joins ACCESS-AD, a Major Initiative Funded by the European Commission, Through the Clinical Evaluation of Blarcamesine as Part of a Precision Medicine Approach in Alzheimer’s Disease • GlobeNewswire Inc. • 01/13/2026 12:30:00 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 01/09/2026 10:26:26 PM
- Edelson Lechtzin LLP Announces an Investigation of Anavex Life Sciences Corp. (NASDAQ: AVXL) and Encourages Investors with Substantial Losses Contact the Firm • PR Newswire (US) • 01/09/2026 01:13:00 AM
- Anavex Life Sciences Appoints Senior Vice President Global Head of Neurology • GlobeNewswire Inc. • 01/08/2026 12:30:00 PM
- Anavex Life Sciences Receives FDA Feedback on Alzheimer’s Disease Program • GlobeNewswire Inc. • 01/06/2026 12:30:00 PM
- Anavex Life Sciences Submitted Request for EMA to Re-Examine Its Opinion • GlobeNewswire Inc. • 12/18/2025 12:30:00 PM
- Anavex Life Sciences Provides Update on Regulatory Review in the EU for Blarcamesine to Treat Early Alzheimer’s Disease • GlobeNewswire Inc. • 12/12/2025 09:05:00 PM
