NorthWest Biotherapeutics Inc (NWBO)

[Lykiri]

Flipper44,

This is from a GBM patient blog:

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In order to produce DCVax-L, two to three grams of tumor tissue are usually required to make the eleven-shot, three year cycle of injections. If the tissue is frozen (only for the UK Specials Program) it must be flash-frozen without any chemicals or preservatives and not preserved in saline or paraffin (most tissue banks preserve tumor tissue in blocks of paraffin). Also, some surgeons use Gliadel wafers. These wafers are soaked with a type of chemo which is meant to poison tumor cells, and are placed in the tumor cavity in the brain when the tumor is surgically removed. If Gliadel wafers were used, then DCVax-L will not be available as a treatment option because the chemo leaching from the wafer will also kill immune cells which enter the tumor cavity to fight residual tumor cells.