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Re: IgnoranceIsBliss post# 164428

Saturday, 12/01/2018 1:27:49 PM

Saturday, December 01, 2018 1:27:49 PM

Post# of 425850
Some argue that this trial needs to be run to completion. Why?

I understand an outcome trial makes sense to run it all the way as with time arms separate more. The more the arms separate the more vascepa will be valued.

Evaporate however seems to be a mechanistic trial. It’s objective is to determine how the drug works. Once you reach statistical significance you have your answer and that could happen at the interim analysis. Further plaque reduction with time will not add value to vascepa so what would be the value to run it to completion?
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