NorthWest Biotherapeutics Inc (NWBO)

[Rkmatters]

It must be within 3 months according to the protocol. Typically once a patient progresses, 5-7 months later they die. Sadly, there isn’t any approved treatment that extends survival after progression. Anyway, they need to administer while a patient is healthy enough to receive the injections.

From the protocol:

Treatment Schedule after Confirmed Progression and Crossover
• Patients will receive up to 10 DCVax-L injections at days 0, 10, 20, and months 2,
4, 8, 12, 18, 24 and 30. Day 0 is the date of the first immunization and must occur
within 3 months of crossover (date of confirmation of disease progression). For
the immunizations at days 10 and 20, the variance may be ±2 days but the
minimum interval between injections must be at least 9 days. For the
immunizations at months 2, 4, 8, 12, 18, 24, and 30 the variance can be ±1 week
with a minimum interval of 6 weeks between injections.