NorthWest Biotherapeutics Inc (NWBO)

[Rkmatters]

Hypoxia significantly inhibits the infiltration of immune cells into tumor tissue. Bevacizumab is believed to normalize tumor vasculature and decrease tumor hypoxic area. Mesenchymal patients have varying degrees of Tumor infiltrating lymphocytes (TIL) before therapy. The vaccine is said to increase TIL afterwards. The combinations of these two therapies could be enhance immune response infiltrated into tumor. They already have historical data on how long patients survive with salvage therapies after progression. I have no doubts whatever that the two in combination will be better than Avastin alone. None.