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Re: Basin Street Blues post# 197251

Wednesday, 11/14/2018 11:29:29 AM

Wednesday, November 14, 2018 11:29:29 AM

Post# of 688913
Basin Street Blues,

I am with you about a potential range because there is a 36 month shelf life for the vaccine and the vaccine is made before official enrollment begins. The protocols say up to 36 months of treatment and followup. Technically the trial would end at that point (full planned for data set based on protocols). This time frame means the trial has ended by now and adjudication of PFS began at data freeze if that path was chosen. If ongoing negotiations about reimbursement are the holdup then any improved benefit seen by later enrolled patients could be a sticking point for unblinding. Hopefully that has been mostly taken care of by now based on an agreed to pricing ladder that matches actual derived benefit in the overall and subtype populations. NWBO has a number of irons to put in the fire asap and I believe credited benefit for reimbursement and competitive purposes is key for how fast they will be able to move forward with minimal dilution. Best wishes.
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