Biotech Values

[rfj1862]

I think most people now believe there is cell killing with TKIs too. When you disrupt the mutation driving the cancer apoptosis may kick in.

We probably shouldn't be discussing TKIs like they are a homogeneous class given the diverse array of targets. I think we're getting a little granular here but I would think that the apoptotic mechanism would almost certainly need to be shut off earlier than the genetic event that initiates dysregulated cell division.

But whatever it's all handwaving, you may well be right for at least some TKIs.