Amarin Corp Plc (AMRN)

[sts66]

Dumb question maybe, but could be important to some of the millionaires who may be cashing out some stock to treat themselves - how exactly do you pay the IRS estimated taxes for a quarter? I mean say you sell enough to make a couple hundred grand in profits - it's not like you should (or can?) write the IRS a personal check and mail it to them, too risky it may get lost or stolen - I'm thinking you'd need to do some kind of wire transfer, maybe directly from your broker to the IRS?