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Re: jessellivermore post# 221316

Wednesday, 10/10/2018 11:19:46 AM

Wednesday, October 10, 2018 11:19:46 AM

Post# of 251612
Hi, JL. RVNC's RT002 appears to attenuate diffusion from the injection sites, as compared to Botox and other Botox-like type-A botulinum toxins. This increases the density of localized neurons that are paralyzed before the botulinum toxin is cleared by the system, which is perceived as a longer duration of action at the injection sites.

Simply using a higher dose doesn’t accomplish the same result because of increased side effects such as ptosis (e.g. for glabellar-lines treatment) or dysphagia (e.g. for cervical-dystonia treatment).

I’m pretty sure we had this discussion a few years ago.

p.s. Congratulations on your AMRN gains!

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