Anavex Life Sciences Corp (AVXL)

[nidan7500]

Jimmy Mc:

thus should have different parameters for calcium homeostasis mediated by *drumroll* mitochondria and the ER

Jimmy, thanks for your posting. Your process addition is a critical one IMO as it points to just how much research of CNS Homeostasis details has been done over decades with no clear application or said differently..."So What", these are proven facts dismissed as anecdotes, until now. We can provide a place for this knowledge to be applied.

This is a stretch but here goes...( I am not even qualified to ask the question...BUT). With CNS cellular Homeostasis as goal-platform for thinking: Will Precision medicine and will leadership from biopharma like Ananvex finally provide a research focus for the galaxy of CNS cellular factoid theorists to actually prove something? I claim that the Amyloid Thesis big money boys not only controlled the FDA etal resources but also the collective thinking in CNS diseases world. The O2 has been sucked out of the room for decades. That is at least a partial explanation, IMO.

As you point out many, many useful facts have been generated and left disconnected, floating w/o a home. If pursuit of CNS cellular homeostasis becomes an initiative ,and with the use of new AI tools, the universe of knowledge and research facts already available may be gathered, focused and properly evaluated. If nothing else the body of knowledge of things , "we know we don't know", can be defined and better put to use. As Dr.M. has said, he is not driven by a thesis (which obviates the need for additional thinking, IMO). Not only can Anavex deliver CNS disease treatments but it might also serve as an empowerment platform-model for whatever follows. Do all the verified and validated CNS bio-theories actually exist in one place?