Saturday, September 15, 2018 12:24:04 PM
Your post is perfect! If we receive reports form any of the three clinical trials that indicate the link below (quote from your post) is being established in any of those trials, Anavex will attract immense interest.
"Editorial:
Once they establish the link between a response in those patients with the gene variants and none in those without, they have legitimized those as biomarkers (like a cholesterol test), as Missling states: it is necessary to have the variants and non variants in the trial in order to use the non variant as a control (that, indeed, the drug does not work) so that the biomarkers can be recognized and proven as biomarkers."
Everyone will be monitoring the Parkinson's Dementia trial in Spain for signs of whether Anavex is getting the hoped for response. Interim trial reports that give any indication that this link is again being established will create much excitement. So far, the PDD trial is the shorter of the two announced trials. I believe it is likely we may know something from that trial as opposed to the AD phase 2/3 trial, but we may receive news from Australia as well.
I would mention Rett except trial approval has not been announced, and comment abou it may invite contentious and unproductive discussions. However, I certainly do not rule it out.
Thank you for enlightening this board.
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