Anavex Life Sciences Corp (AVXL)

[nidan7500]

Dr. Peter Senge has done great work in systems dynamics @MIT. (his book, "The Fifth discipline" is helpful). He describes a number of archetypes, many of which might be applied here. One of his archetypes is called, " fixes that fail". One characteristic is a process that keeps getting repeated in spite of unintended consequences, (previous failures) usually w/ follow up delays. (nothing new) People who have found themselves in one of these management death spirals will tell you how hard it is to detect your own process failures. Talon would tell you that the term "Death spiral" has a very specific meaning for pilots and it is easily analogous to what has happened in the CNS disease space. Hint, pulling back on the stick while in a death spiral only accelerates the out of control dive condition, the opposite of what seems intuitive. IMO, the Scientific method of reasoning begat the FDA trials process, the rest is history. Somehow they never understood they were in a death spiral, which BTW is what killed John Kennedy Jr. off Cape Cod.

So, let's all move on then. Precision Medicine-Science looks to me to be the next version of the Scientific Method...but...it now includes breaking through the walls of, "Not knowing what we don't know". Well, we are going to find out w/the help of some excellent new AI tools and with a process team who have challenged the establishment and (so far) are still alive. The PROCESS is what matters.