The Inflammation Factor
Yes, the “waste proteins” of Alzheimer’s, the beta-amyloids and tau tangles, are decidedly inflammatory, as proven in murine studies. Inflammation of nerves and nerve tissues is always problematic. When inflammation is well-controlled and properly restrained, it initiates and modulates appropriate immunological attacks on extrinsic pathogens, bacteria in particular; in some cases viruses. Well and good.
But inflammation can call out too many immunological defense troops (empowered leucocytes) who then fail to discriminate between invading, infecting pathogens from normal body cells and tissues. Not only are pathogens “controlled,” normal cells and tissues are attacked and slain. One needn’t know much biology to imagine what results when nerves are so attacked.
The author states, “It seems that if given early enough ANAVEX 2-73 can stop or even reverse progress of the disease.”
If Anavex 2-73 can cause neurons to accurately create proteins, by allowing endoplasmic reticula to function normally, enzyme proteins will be folded into their proper, functioning shapes, thereby creating normalized, healthful chemistries within the neuron. No disease onset.
Personally, I’ve contended this myself a number of times. Administering Anavex 2-73 after beta amyloid and tau wastes have profusely accumulated and induced neuron-destroying inflammation may not be useful. The wastes have accumulated, induced inflammation, and affected neurons cannot be salvaged. But start the treatment early, before waste proteins have much accumulated, and the normalized protein enzymes from the Anavex-restored endoplasmic reticula will maintain, even restore neuron function.
Why wait to treat Alzheimer’s with Anavex 2-73 until severe, irreversible damage to neurons and nerves has occurred? Treat at the very first signs of Alzheimer’s, before irrevocable damage has occurred, before waste proteins have accumulated to any degree.
With 300 people taking Anavex 2-73 in the upcoming trial, a computer’s plotting of outcomes should reveal if this scenario is accurate. If it is, those taking the drug at earlier stages of the disease will have better results. Those at more advanced stages will have reduced positive outcomes.
I’ve also contended that eventually Anavex 2-73 may be universally prescribed to virtually every one, at some yet to be determined age, say, age 50. With that, any of the central nervous system diseases (or others) can be prevented from developing. Treated and prevented at the start, before any irrevocable, chronic damage has been done.
When you were ten, your mother in winter used to say, “Better put on your coat. We don’t want you to catch a cold.” Will physicians sometime be saying to their mid-aged patients, “Well, I see you are approaching your 50th birthday. Time for you to start taking an Anavex pill each day. We don’t want you to develop any of those horrible diseases people used to get?”
AI
