Amarin Corp Plc (AMRN)

[invest2992]

It's an interesting journey we've been on for the last 5-6 years with Amarin/Vascepa, depending on how long you've been riding this horse. When we started, V was a superior Trig suppressor to Lovaza, because it didn't raise LDL, and we had that large market in front of us. Then, when the FDA dropped trigs as a significant bio-marker we turned to the inflammation suppression properties of V through the improvement in the EPA/AA ratio as proposed by Dr. Sears and others. Now we have come full circle and again are trumpeting V's trig lowering properties, with trigs now recognized as an independent factor in CVD.
All of which leads me to the conclusion that we don't yet fully understand V's MOA, which may be further complicated if it proves effective for other indications. For instance if it is in fact effective for DES, it is probably not because it reduces trigs. And if it proves effective in the fight against Alzheimer's, will it be because it reduces systemic inflation? These are questions I'm not smart enough or educated enough to answer.
My approach is simpler. If it works, take it.