Someone asked me the other day why I’m so sure this is going to be a successful trial given the current knowledge we possess of A2-73. I can Compartmentalize this question in to many categories of check the box...
1.) The SR-1 receptor is virtually unchanged over thousands of years of evolution across all species of mammals and present in all mammals which tells you not only is it important but there is virtually no variation .i.e. what works in a mouse will work in a human; plain and simple do to the fact we know it crossed the blood brain barrier in both patient models the same results are virtually guaranteed...although possible to be different, highly unlikely....also the trial approach and theory is not a repeat of previous failures.
2.) Non existent academic rebuttal papers disproving or attempting to disprove/discredit the science.
3.) Non existent competition/SOC, along with major players deciding not to compete at all.
4.) Australian government, Micheal J. Fox, Rhett’s foundation which are legitimate players backing this small company...this doesn’t happen randomly very often....governments don’t listen to small businesses unless it’s legit or we have an inside track.
5.) Caregivers requesting extension of trial not the other way around.
6.) Whether you want to believe it or not we have a CEO who has already taken a small company and made it worth billions in the past, so he knows what he is doing for long term success.
7.) The BOD is made up of well respected scientists in their field.
8.) we have no debt, we are positioned to finish our trials for the next two years and have access to an ATM if need be moving forward.
9.) Governments around the world are going to be desperate for an answer to a problem that could collapse health care so they will be highly motivated to fast track if we have the goods.
10.) I’m risking less than the price of a hamburger per share.
Put this many positives together in alignment says only one thing...success is far more likely than failure.
I honestly don’t see how anyone looking at this objectively can read so many positives as a negative...you might be conservative and waiting for final confirmation with trial results and that is fine, but to try to spread FUD based on fairy land thoughts is ludicrous....and only would happen if your short, working for those who don’t want AVXL to succeed (no moral code type individuals) or you really have no excitement in your life and maybe need to grab a beer and try living a little.
Have a good one amigos, and stay Frosty
