NorthWest Biotherapeutics Inc (NWBO)

[Lykiri]

Sentiment,

I agree that the longer drop counts as 2 and sometimes as 3!

You indicated every step down with little red dots and i see 18 between 30 and 36 months.
The last one is at 36 months and a few days.That's the moment one of the 44 patients died.

The first red dot is not at 30 months but at the end of month 29.

Conclusion: speaking about that section between 30 and 36 months:

7 censored and i believe alive at the time of the analysis.
16 died.(67-44=23 and 16+7=23)

Your post 185633

I count 25 red dots on the section between 24 to 30 months.

That red dot at 30 months belongs to this section. So you have 25 + 1= 26 died.

We know from ASCO 2018 that 115 patients lived 24 months or more.
115- 67 (30 months)= 48 patients.
48 – 26(died) = 22 censored between 24 and 30 months and i believe alive at the time of the analysis.

let's find out how many patients had surgery before March 15, 2015.
(Marnix Bosch did not give us that number)

331-223 (at 30 months) = 108 patients between September 15, 2014 and August 15, 2015.(11 months) That is an average of 10/month.

223 + 60 = 283.

If i look at the Enrollment Timeline i see 87% enrolled June 15, 2015 (3 months after surgery)
https://www.nwbio.com/Boston-slides-31Aug2017-v0.5.pdf

87% of 331 = 288

take the average of 288 and 283 = 285
placebo= 95
treatment=190

So where are the 108 patients alive at the OS curve.(at the time of the analysis)

I guess that 3 died of the 44 patients who lived for at least 36 months. That’s 41 alive.(after the 36 month timeline)

Between 24 and 36 months: 22 + 7 = 29 alive.

Conclusion: 108 – 29 – 41 = 38 patients alive between 19 and 24 months.

38 patients of a group of 46. (331-285=46)
Placebo: 4 (99-95)
Treatment: 42 (46-4)