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Re: blue_skies post# 185224

Monday, 08/06/2018 10:23:33 AM

Monday, August 06, 2018 10:23:33 AM

Post# of 699233
I am on the other side of this. I believe they HAD to do a crossover from placebo based on the positive results they were seeing, and it would have been inhumane not to. But, since the trial was constructed to show a difference between the two groups, they had to extend to show the separation on long tail. I also believe that there had to be agreements or understanding with trial regulators that if they allowed crossover, and it hurt the trial results because of the crossover, there would have to be consideration.
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