Anavex Life Sciences Corp (AVXL)

[sokol]

Yes, Anavex realizes the problem it is up against, and the way to approval is outside the United States. That has been my belief from the time I first purchased Anavex shares four years ago. I keep my personal life private, but some of what I write here is based on my lengthy experience in . Australia, Spain, and possibly some other venues may be favorable. I know Japan has been mentioned as one, but I think Anavex has the same or similar problem with Japan. Insidious powerful interests are present in Japan as well.

Company interests do not necessarily coincide with your interests, and that is true in all aspects of business whether it be pharmaceutical, energy, agricultural, chemical, etc. Corporate interests in the United States and many other countries influence the public with their media campaigns and most importantly influence the governments. How do they influence government? They do it through campaign funding, lobbying and regulatory agencies. Just one example (there are many) the opioid crises was created with the help of Congress. One member of Congress most responsible was from Pennsylvania. He was later appointed Drug Czar to "combat" the opioid crises -- that member of Congress would still be there but for exposure on 60 Minutes. Nevertheless, the committee to combat the opioid problem is centered in New Jersey where major drug companies are located, and drug company representatives serve on the committee. Check out what 60 Minutes exposed and also see this: NYTimes: "Origins of an Epidemic: Purdue Pharma Knew Its Opioids Were Widely Abused"
https://www.nytimes.com/2018/05/29/health/purdue-opioids-oxycontin.html?smprod=nytcore-ipad&smid=nytcore-ipad-share

There are many tactics that may be employed to prevent competition from an existing product or service or new ones. Example, larger companies have sometimes bought a smaller competitor and shut it down. If you are Dish, you might buy cable franchises from towns or cities and never deploy the cable service. I think it is a good thing that Anavex has taken steps to prevent this tactic.

Along similar lines, check out the practice of "evergreening". "Evergreening"

"Most New Drug Patents Are for Old Remedies", Research Shows by Cynthia Koons

The U.S. patent system was designed to protect new innovations, but drugmakers are more often than not using it to protect old ones.

https://www.bloomberg.com/news/articles/2017-11-01/most-new-drug-patents-are-for-old-remedies-research-shows

Major drug companies are more focused on protecting their blockbuster drug lines (billions of dollars per drug) than they are in innovation. A company does this because their drug prices may then be much higher due to continuation of their monopolies. Plus, with older drugs, costs of development/acquisition, etc., have been recouped, the active ingredient may be cheaper, and you may approach something like a 90%+ profit margin.

I will end on a note of optimism. I do believe too that there are good people that work in government and major corporations. Plus, if Anavex's drugs are proven and approved in Australia, Spain or wherever, this will be the pressure that will allow the drugs to be available everywhere. And then, maybe Anavex will join the powerful corporate interest, and the cycle will repeat itself.