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Re: rayovacAAA post# 158499

Thursday, 07/19/2018 3:02:07 PM

Thursday, July 19, 2018 3:02:07 PM

Post# of 468026
By “science” I mean the approaches taken and the reasons for them. Obviously, people in the Anavex camp are expecting to hear about trials based on precision medicine stemming from genetic biomarkers identifier from a previous trial cohort and work with Illumina’s next generation genome sequencing expertise.

We have already PR’d news to that effect and discussed it in conf calls.

In the case of Biogen, the approach they have taken is amyloid clearing to restore cognitive function or slow decline as stated in a rather show stopping PR they recently released.

That seems very clear to me as what expectations are from each company although the overlying grit will be dusted off at the trials.

The fact that neither direction is a positive in absolute terms means we are at a scientific fork in the road about the cause of Alzheimer’s. That’s muddy.

As to “if the science were crystal clear why even have a conference? To rehash something we already know?”

Please refer to AAIC conferences in which amyloid plaque was presented as an extremely promising path forward to curing this disease finally, and subsequent trial outcomes from the years 1997-present.
What was nonsensical in my opinion was the need for a Conference during those years, imo. Nothing new under the sun was ever presented with a successful outcome; very few, if any, deviations from epic trial after trial of the same methodology which failed year in, year out. Must have been quite suspenseful attending those? Announcements not advancements - ever, sorry.

These were the salad days of the BP’s and the Conference was the Annual Amyloid Clearing Fish Fry and Bake Sale.

With respect,
Bio

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