Anavex Life Sciences Corp (AVXL)

[drv17]

Kentucky - Following is a copy of the World Wide Patent Application for the process and composition of A2-73 and it's metabolite A19-144.


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29. (WO2017013498) CRYSTAL FORMS OF TETRA-HYDRO-N, N-DIMETHYL-2, 2-DIPHENYL-3-FURANMETHANAMINE HYDROCHLORIDE, PROCESSES FOR MAKING SUCH FORMS, AND THEIR PHARMACEUTICAL COMPOSITIONS

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Pub. No.: WO/2017/013498 International Application No.: PCT/IB2016/001181
Publication Date: 26.01.2017 International Filing Date: 19.07.2016
IPC:
C07D 307/14 (2006.01), A61K 31/341 (2006.01), A61P 25/28 (2006.01)

Applicants: ANAVEX LIFE SCIENCES CORP. [--/US]; 51 West 52nd Street, 7th Floor New York, NY 10019 (US)
Inventors: YORK, Peter; (GB).
LEONARD, Lucy, Anne; (GB).
LEDGER, Daniel, Mark; (GB).
DAINTREE, Linda, Sharon; (GB)
Agent: SAUNDERS, Thomas, M.; POLSINELLI PC 100 Cambridge Street, Suite 2101 Boston, MA 02114 (US)
Priority Data:
62/195,486 22.07.2015 US
Title (EN) CRYSTAL FORMS OF TETRA-HYDRO-N, N-DIMETHYL-2, 2-DIPHENYL-3-FURANMETHANAMINE HYDROCHLORIDE, PROCESSES FOR MAKING SUCH FORMS, AND THEIR PHARMACEUTICAL COMPOSITIONS
(FR) FORMES CRISTALLINES DU CHLORHYDRATE DE TÉTRA-HYDRO-N,N-DIMÉTHYL-2,2-DIPHÉNYL-3-FURANE-MÉTHANAMINE, PROCÉDÉS DE PRÉPARATION DESDITES FORMES, ET COMPOSITIONS PHARMACEUTIQUES LES CONTENANT
Abstract: front page image
(EN)Polymorphic forms of tetrahydro-N,N-dimethyl-2,2-diphenyl-3- furanmethanamine hydrochloride (ANAVEX2-73) and a metabolite of tetrahydro-N,N-dimethyl-2,2-diphenyl-3-furanmethanamine hydrochloride (ANAVEX2-73) are disclosed and characterized. Compositions and method for treatment of Alzheimer's disease that includes the polymorphic forms and metabolite of tetrahydro-N,N-dimethyl-2,2- diphenyl-3-furanmethanamine hydrochloride (ANAVEX2-73).
(FR)Cette invention décrit et caractérise des formes polymorphes du chlorhydrate de tétrahydro-N,N-diméthyl-2,2-diphényl-3-furane-méthanamine (ANAVEX2-73) et d'un métabolite du chlorhydrate de tétrahydro-N,N-diméthyl-2,2-diphényl-3-furane-méthanamine (ANAVEX2-73). Des compositions et une méthode destinée à traiter la maladie d'Alzheimer qui comprennent les formes polymorphes et le métabolite du chlorhydrate de tétrahydro-N,N-diméthyl-2,2-diphényl-3-furane-méthanamine (ANAVEX2-73) sont en outre décrites.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)


Also from a Polarbear77's post#120449

[i

]Because they've contracted with a world-class team of international patent attorneys to painstakingly document and protect its IP in a wide range of indications and chemical formulations during a process that must have utilized a tremendous amount of time and Company resources. Why in heavens would they waste everyone's time and money if the endeavor was fruitless?