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Re: None

Friday, 07/13/2018 5:30:44 PM

Friday, July 13, 2018 5:30:44 PM

Post# of 458440
Questions I ask as we approach AAIC.

1. Would Dr.M. pull in an AD trial and announce it before Rett trials if he did not have an AAIC slam dunk? (no-IMO).

2. Is it likely he will show a direct link w/Biomarker analysis to responders? (Yes-IMO)

3. Will Dr.M. do a presentation at AAIC that shows a clear link to markers w/PET results that support patient related responses? (Yes-IMO)

4. Is it likely he will present evidence (RWD,RWE) of previously confirmed AD patient recovery, like video, AD Chorus, other. (yes-IMO)

5. Is it likely the AVXL team will present further evidence from Academic and Healthcare sources which further validate efficacy claims? RWD, RWE. (Yes-IMO)

6. Is it likely the FDA-NIH will respond favorably to new AVXL CNS disease initiatives? RTT, other (Yes-IMO)

7. Do you expect strong WS/BP/Fake Media support-praise and appreciation for the AVXL AD results, which they have endeavored to achieve for decades and have failed miserably to do? (No-IMO)

8. If BIIB claims are not validated by FDA should they be directed to stand down until they do so? (yes-IMO)

9. Is this a David v. Goliath Grudge Match PR showdown between AVXL and BIIB? (yes-IMO)



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