Thursday, July 12, 2018 7:26:49 PM
Article: Combination of Immune Cells Improves Chances of Successful Immunotherapy.
“Krummel’s lab found a kind of immune cells called stimulatory dendritic cells (SDCs) were required for more robust T-cell responses. Without SDCs, T-cells were unable to respond effectively to checkpoint inhibitors.
However, for SDCs to be recruited and survive within tumors, another kind of immune cells was needed. Those are the NK (natural killer) cells, and usually act as first responders to detect cancer cells.
“One of the fascinating discoveries here is that we’ve long known that natural killer cells — as their name implies — can also kill cancer cells directly,” Krummel said. “But here we are discovering that their power doesn’t lie just in their ability to eliminate threats, but also in their ability to communicate with other immune cells.”
https://immuno-oncologynews.com/2018/06/29/combination-immune-cells-improves-immunotherapy-success/
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