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Friday, 07/06/2018 7:40:31 AM

Friday, July 06, 2018 7:40:31 AM

Post# of 701767
Statistical significance...

One of the most interesting things I’ve contemplated recently is primary and secondary endpoints along with statistical significance. I think most investors here know that our likelihood of achieving endpoints is pretty high based on blended data and historical data. But I’m wondering if the wait at this point is being done to achieve lower p values and greater statistical significance. If (more like when) the naysayers attack positive endpoints, they’re going to do it with statistical significance. The SAB understands that with the crossover arm, statistical significance may be harder to achieve without fully mature data. Can anyone comment on this?
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