<blockquote><span style="font-size:90%">Quote:<hr/><i>So... what to make of all that? Well, it seems the ABN thinks the appraisal should be completed following the publication of the P3 unblinded results. <span style="color: red">However, the action is to note first, that they plan to publish guidance within 90 days of marketing authorization,</span> and second, they will take this into consideration as appropriate. Then pertaining to the second set of comments, the action is that NICE considers the technology appraisal necessary at this stage. </i></span><hr/></blockquote> <br /> Yup. <br /> <br /> And they previously stated they were taking this date (approval) under guidance from NWBO. <br /> <br /> But that is now not going to happen within a year even if the trial works. So we will almost certainly see this either punted down the road, or cancelled. <br /> <br /> Any bets?