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Monday, 06/04/2018 10:09:39 AM

Monday, June 04, 2018 10:09:39 AM

Post# of 470865
One good thing about the precision medicine approach/thought process is that the sponsor is expected to have a rational, fact based story to tell.
That compared to 20+ years of, let's take some population of known sick people and try XXXXZZZZXXX. And, If we try a big enough sample we should get some responses, and if we have to we can just expend the sample size. Hey, what could go wrong?

BTW, it looks like the breast cancer (very wealthy sponsor) Chemo people have hit a wall a lot like the Amyloid guys. Huh, well, "never mind the Chemo is not required, in fact it might be harmful" my emphasis. Maybe getting them to stand down was done a lot like the Amyloid guys.

Getting technical facts to support a thesis and then demonstrating efficacy is not an easy thing to do, but it will be a lot cheaper to do, faster to determine if/when real progress has been made and that it is sustainable. All of this comes from knowing what you are doing, vs shotgunning. And, when you are done you can actually use the results to learn something positive. Ain't science grand.
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