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Re: beartrap12 post# 171256

Thursday, 05/03/2018 10:02:22 AM

Thursday, May 03, 2018 10:02:22 AM

Post# of 700691

Me: PFS progression, did we find people who had not really progressed but because of pseudoprogression, were put down as having progressed?

Linda: I'm not sure where you're getting that from ...us going through this or that process.
We haven't said anything publicly about PFS or progression. We haven't talked about having gone through this process or that process. We haven't spoken about the subject yet. That's something will be... that lies ahead, that we will be speaking about in the future. But not that I'm aware of, we haven't spoken about it yet. So you have to stay tuned.



I want to emphasize this comment of Linda's, which I didn't pick up correctly at the meeting, but caught on tape. She appears not to know what I'm talking about, which I originally took out of context and thought she didn't know anything about a process to reclaim patients who were mis-diagnosed as PFS, but were really pseudoprogressors. But as I typed her actual comments now, I see that she's actually surprised I knew they were going through that process because it hadn't been publicly talked about. I know I had a conversation with Les after the 2016 meeting where I had the impression that's what they were checking....misdiagnosed patients. It's also something we have discussed on this board. What she actually said was they would address this question in the future. And she used that term, "Stay tuned" in what sounded positive. I think this is a good indication that at least a few patients marked as progressors, were actually pseudoprogressors, and that is being corrected or discussed with regulators, at least. This is just my interpretation of the exchange, so please don't hold me to it if it doesn't turn out to be true. In the meeting, I think my question threw her off because she wasn't ready to talk about this subject, and then the beginning of her answer, her stating she didn't know where I got that information, threw me off my game so I missed the reality, which is she truly didn't know where I got that information, not that I wasn't correct.
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