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Re: Mikesc post# 148312

Friday, 04/20/2018 12:03:30 PM

Friday, April 20, 2018 12:03:30 PM

Post# of 461261
Thanks Mike...would like to see AVXL pull in any plans...unclear what this (PD,RS,AD) trifecta means in context of new Adaptive Trials rules. When results start to flow then special recognitions (BTD, etc.) may be in order.

“We are excited to progress our program to Phase 2, with a focus on the many patients with Parkinson’s disease dementia, and we remain focused on the discovery and development of potential treatments for neurological diseases with unmet needs, including Alzheimer’s disease and Rett syndrome,” Missling added.
Anavex filed an updated investigational new drug application to the U.S. Food and Drug Administration (FDA) earlier this year for a double-blind, Phase 2 study evaluating Anavex 2-73 in Rett syndrome. If approved, this trial is also expected to open in late 2018.
The company plans to open a Phase 2/3 trial of Anavex 2-73 in up to 300 people with mild-to-moderate forms of Alzheimer’s disease. A Phase 2a dose-escalating study (NCT02244541) involving 32 people with probable Alzheimer’s was conducted at sites across Australia.



https://parkinsonsnewstoday.com/2018/04/20/anavex-planning-phase-2-trial-of-potential-parkinsons-dementia-oral-therapy/?utm_source=PAR+E-mail+List&utm_campaign=78e7cd4b2e-RSS_WEEKLY_EMAIL_CAMPAIGN_DAILY_US&utm_medium=email&utm_term=0_62dd4fb5e3-78e7cd4b2e-71626601
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