Saturday, April 07, 2018 10:44:52 AM
Xena...WOW , good stuff.
IMO, a learning process driven by peeling back the steps/sequence (gradual/spontaneous) by which cognition is snuffed out is critical. The reverse engineering of the whole sequence will certainly get us to the root cause. If M. is correct and the restoration of CNS cellular Homeostasis suggests cognitive health and behavioral normalcy then this kind of imagery might be used to validate such a correlation and to verify restoration. We would expect any restoration would vary from pt to pt measured over time/compared with controls of course. Using reverse engineering techniques/thinking keeps the ball on the field all the time, we expect to see the cause/effect virtually real time. If AD is progressive w/time then the reverse must/might also be true. There has been anecdotal evidence that some AD pt's recover, but what about the rest? Does partial restoration count, how is it measured? RWE/PET and cognitive testing will certainly be factors in AD future trials testing.
I declare as a volunteer for the continuous frat boy control branch of the trial.
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