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Re: Hagrid post# 145880

Thursday, 03/29/2018 11:44:48 AM

Thursday, March 29, 2018 11:44:48 AM

Post# of 463574
We need to be aware of the time bubble which most biotech-pharma labs/development organizations live in. H/W medical device people(part 820) have H/W regression curves/methods which can be used to safely accelerate failures, for example. They are able to accelerate H/W failures. The bio clock variable is experiential, some may have clocks that run synched with the rest of us but often bio clocks are not synched. Consequently they might have 3 yrs to wait for results in the lab while the rest of us decompose in 1 year. All of this gets completely screwed up when someone stops the train and requires a restart(Precision medicine for example). AVXL may be slower than even the normal clocks due to the nature of CNS diseases. Hopefully, RETT will soon accelerate the clock somewhat. It is all very frustrating as we await evidence-results. IMO, the clocks will probably be reset/synched up when we start to see PII timelines/results. I have seen nothing that predicts how much time it will take to demonstrate efficacy or if the normal clocks will even matter much. Many of us expect quick feedback though.

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