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Re: The Mongoose post# 145319

Thursday, 03/22/2018 6:02:12 PM

Thursday, March 22, 2018 6:02:12 PM

Post# of 463570
Thanks Mongoose

3 things are playing in to this silence issue which will be resolved soon

. Depending on how the RETT trial is conducted and reported this could be the high leverage PR we need. If the CNS cellular Homeostasis (silver bullet) card is played we will be a hot item. If not, then very important but not rocket fuel, IMO.

I am a Dr. M. believer myself. Your point on German being his heritage and first language is probably a factor in how he reasons and communicates but he does extremely well IMO. I studied German language myself for 4 years and all I got from it poor spelling for English, destruction of any sense of syntax I might have otherwise had and the knowledge that I can sing most Christmas carols in German.

I also agree that when Rett trial is done, with almost any degree of success, we will be able to make the point on THAT RESULT IS A BINARY EVENT in CNS medical science. IMO, depending on what happens and how it is handled around connecting the CNS dots everyone wins, except the amyloid plaque boys. Then, Dr. M. can come out and talk his guts out, truly a thing of beauty. In the meantime he needs to let the world know what the plans are, even though the FDA processing is in the way (IMO). He can do a press conference in German and rely on translators to fill in the nuances.

This has been an important investment for me for a lot of reasons. We all have some level of doubts but I think the science information has been valid and consistent, without contradiction. We have a very solid SAB and support staff with major outside support. All we need to do at this point is ACT LIKE WE BELONG IN THE ROOM, which admittedly is not easy with the BP bunch but it must be done.

Thanks Mongoose for your thoughts. We are going to do well with this.
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