Thursday, March 22, 2018 8:00:41 AM
1. I do agree we are caught in some kind of parallel universe comm. zone time warp made up of FDA and Govt/politics and the enormous need for REAL HONEST MEDICAL SCIENCE. Three years ago before I ever heard of A2-73 I would have defended the FDA and the BP systems established for clinical trials and scientific methods in play. Over time w/study I have begun to seriously question how the process is working and in fact am now convinced the process is seriously flawed, perhaps even criminal in areas. Having spent time as a lab rat and much time around regulatory practice/financial reality I now see the failures around AD and other CNS diseases as poorly executed, expensive, political, frauds on taxpayers and sick people. A child could ask some basic questions in retrospective analysis and conclude they should have stopped what they were doing 10-20 years ago. The good news is that entire level of thinking and statistical modeling is gone or is going away (they will just not admit it yet). We need medical/scientific facts, not statisticians and smoke. Trials will now be managed w/science and thankfully using RWE, which must be easily and credibly explained and proven.
2. AVXL is a very small company and would easily be destroyed by just one error in judgement. Timing, scientific events, PR's, political , financial, mistaken sequence...and the list goes on. The problem we have in dealing w/this environment is we have very little ammo and there are lots of targets. Dr. M. must find a communication tactic that works for him and that is effective, being silent is not a communication strategy, even though he is good at it. IMO, eventually silence becomes a bad habit and eventually it adversely impacts credibility.
3. Dr. M. must capture and present the context we are in more effectively. He can do this w/o betting the farm by being open about our A2-73 testing strategies and methods. And he must do that right away while all the competition are still down in their bunkers. The FDA and BP are clearly scared shatless about making a wrong move right now on ANYTHING . Musashi was a great warrior his famous poem on the .."The Pen and the Sword , in ACCORD" , has never been more meaningful than right now in this space. It is time to ACT with superior tactics which IMO will require generous use of RWE and precision medical science. One strong case made w/the FDA will save them from continued humiliation and will rewrite the future on CNS medical science. IMO, AVXL is capable of showing the way.
IMO, the window will close if he does not act soon.
Recent AVXL News
- Anavex Life Sciences to Present at the H.C. Wainwright 26th Annual Global Investment Conference 2024 • GlobeNewswire Inc. • 09/03/2024 11:30:00 AM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 08/06/2024 09:21:05 PM
- Anavex Life Sciences Reports Fiscal 2024 Third Quarter Financial Results and Provides Business Update • GlobeNewswire Inc. • 08/06/2024 11:30:00 AM
- Anavex Life Sciences to Announce Fiscal 2024 Third Quarter Financial Results on Tuesday, August 6, 2024 • GlobeNewswire Inc. • 08/01/2024 11:30:00 AM
- Form 8-K - Current report • Edgar (US Regulatory) • 07/30/2024 09:20:53 PM
- Anavex Life Sciences Announces Translational Biomarker Data for ANAVEX®2-73 (blarcamesine) in Fragile X Syndrome (Major Cause of Autism) at the 19th NFXF International Fragile X Conference • GlobeNewswire Inc. • 07/30/2024 11:30:00 AM
- Form S-3 - Registration statement under Securities Act of 1933 • Edgar (US Regulatory) • 07/29/2024 09:21:49 PM
- Results from Anavex Life Sciences Landmark Phase IIb/III Trial of Blarcamesine Presented at Alzheimer's Association Conference • GlobeNewswire Inc. • 07/28/2024 09:00:00 PM
- Anavex Life Sciences to Present at the H.C. Wainwright 5th Annual Neuro Perspectives Virtual Conference • GlobeNewswire Inc. • 06/20/2024 11:30:00 AM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 06/17/2024 11:30:10 AM
- Anavex Life Sciences Announces Expansion of Leadership Team • GlobeNewswire Inc. • 05/22/2024 11:30:00 AM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 05/17/2024 10:01:00 AM
- Anavex Life Sciences to Present at the H.C. Wainwright 2nd BioConnect Investor Conference at NASDAQ • GlobeNewswire Inc. • 05/14/2024 11:30:00 AM
- Shareholders that lost money on Anavex Life Sciences Corporation(AVXL) Urged to Join Class Action - Contact The Gross Law Firm to Learn More • PR Newswire (US) • 05/10/2024 09:45:00 AM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 05/09/2024 08:35:55 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 05/09/2024 12:00:30 PM
- Anavex Life Sciences Reports Fiscal 2024 Second Quarter Financial Results and Provides Business Update • GlobeNewswire Inc. • 05/09/2024 11:30:00 AM
- The Gross Law Firm Announces the Filing of a Securities Class Action on Behalf of Anavex Life Sciences Corporation(AVXL) Shareholders • PR Newswire (US) • 05/07/2024 09:45:00 AM
- Form DEFA14A - Additional definitive proxy soliciting materials and Rule 14(a)(12) material • Edgar (US Regulatory) • 05/06/2024 10:03:33 AM
- Anavex Life Sciences Corporation Sued for Securities Law Violations - Contact The Gross Law Firm Before May 13, 2024 to Discuss Your Rights - AVXL • PR Newswire (US) • 05/03/2024 09:45:00 AM
- Anavex Life Sciences to Announce Fiscal 2024 Second Quarter Financial Results on Thursday, May 9th, 2024 • GlobeNewswire Inc. • 05/02/2024 11:30:00 AM
- May 13, 2024 Deadline: Contact The Gross Law Firm to Join Class Action Suit Against AVXL • PR Newswire (US) • 04/26/2024 09:45:00 AM
- Contact The Gross Law Firm by May 13, 2024 Deadline to Join Class Action Against Anavex Life Sciences Corporation(AVXL) • PR Newswire (US) • 04/19/2024 09:45:00 AM
- The Gross Law Firm Reminds Shareholders of a Lead Plaintiff Deadline of May 13, 2024 in Anavex Life Sciences Lawsuit - AVXL • PR Newswire (US) • 04/16/2024 09:45:00 AM
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