I don't think the currently running phase 3 in RCC will meet its primary PFS endpoint. And even if it does, I don't think the data will be clinically competitive. They're running against sunitinib / pazopanib but I think newer drugs like axitinib are the real competition. Axitinib has also had some very strong response rate data in the 80% range in combination with PD-1 inhibitors.
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