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Wednesday, 02/28/2018 10:08:52 AM

Wednesday, February 28, 2018 10:08:52 AM

Post# of 462094
The RETT trial start up will help when it happens. So, what's the hold up?

As Talon 38 has been trying to tell us this for a long time..BUT..It's complicated.
Read his linked short paper from NE Journal which outlines how life has changed in IND land and Trial land.

http://www.nejm.org/doi/full/10.1056/NEJMra1510062

After you have read this answer a few questions:

1. If you were Dr.M., which trial method/protocol would you select?
2. If you wanted to optimize A2-73 trial quality would you have a larger or smaller population of patients?
3. Considering new knowledge is being developed every day, when is the best time to start? Start now, or wait for more (now due) information which promises to improve likely best outcome?
4. If we can stop in midstream and redirect, should we? Why/why not?
5. Considering this Rett S. trial will likely lead to an entirely new field of CNS medicine WW. Why not start ASAP?
6. Is this the end of biotech boom-bust investing as we know it or is it just the start of an even bigger cycle?
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