Anavex Life Sciences Corp (AVXL)

[nidan7500]

Whistling past the graveyard. Does 20+ years of failure (99.6%) not present strong proof for NOT DOING WHAT HE IS DOING?

[quoteAducanumab is an injected antibody designed to target beta amyloid, protein pieces that can clump together to form plaques in the brain associated with Alzheimer's. Previous drugs based on the "amyloid hypothesis" have failed to show significant effects.

Mr. Vounatsos said he believed the hypothesis was valid "until proven otherwise" but cautioned against overly high expectations for aducanumab. "It's not one intervention that will suddenly cure the disease. There will probably be different sets of interventions," he said.

Though it doesn't have specific trial plans yet, Biogen is already thinking about combination therapies, he said.

Commenting on Pfizer Inc.'s decision to pull out of Alzheimer's research, Mr. Vounatsos said the field wasn't well-suited to diversified drugmakers that also sell cancer and heart drugs.

"This is our mission," he said. "And so I'm not surprised that some companies decide to opt out. Because it's complex and high-risk, and you can't do that halfway."][/quote]