Monday, February 19, 2018 5:11:14 PM
Yes, w/o question Dr.M. has been on a different path from the start. At first I thought.. well, he has to go down a different path else he will be swallowed by a bigger fish in no time and they may never do anything to evaluate the thesis (homeostasis). Homeostasis was/is a bet the company strategic decision.
He started saying and doing things that BP (w/all their millions/labs/staffs and assets dedicated to the old school) despised. At the time he was the ONLY one heading his way. Eventually the FDA broke the news on new protocols to come...SOON. Now he looks a little better but we need a BTD. IMO, B//P must reconfigure it's trials/testing processes otherwise they will eventually take themselves out of the game. BIIB position on AD trials and zero feedback on MS/A2-73 is a mystery. They can all catch up fast but they will need leadership w/different visions.
Many years ago I inherited a device from an extremely capable engineer who had poured his life into this thing...but he could not get the required results after 19 mos. of day/night trials. He threw his hands up and quit, walked out. It ended up on my desk the next day. I studied the design and it was perfect BUT the base material he was using was not capable of delivering the current blah,blah. I looked deeply into the base material properties and the answer JUMPED OFF THE PAGE at me. I was certain that it MUST WORK. Did some calculations and produced a batch of products w/the new material and they were perfect. That is how I saw Dr.m's claims years back when he was howling at the moon (tip of the iceberg, any day now, all the pieces fit...Homeostatsis) . IMO, he knows this will at least perform for patients in a way that has never happened. It is also possible that the FDA (IMO) sees some of what he sees.
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