Amarin Corp Plc (AMRN)

[biowreck]

Could...maybe this can shed light..

Recall in two Phase 3 trials, Vascepa affected inflammatory markers including hsCRP and Lp-PLA2 while also improving lipid biomarkers. CANTOS and other recently reported studies help to increase our confidence in a positive and commercial outcome for REDUCE-IT. Also, CANTOS, together with other recent CV outcome studies […] have all served to lower the bar with respect to efficacy results, with less than 15% RRR viewed positively even for drugs with significant risks. AMRN has not lowered expectations for REDUCE-IT results, but this lowering of expectations from other studies, we feel, gives a comfortable starting point,” concludes the analyst, who underscores, “According to physicians, an 8%-10% risk reduction in CV events would be considered a success for REDUCE-IT. 15% would be great, and 20% would be exceptional results.”