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Re: LakeshoreLeo1953 post# 140058

Wednesday, 02/07/2018 7:11:12 AM

Wednesday, February 07, 2018 7:11:12 AM

Post# of 462472
As an investor and doing science based DD, the PR is very good.

I shall look very much forward to the presentation on the genetic findings.

The Company has completed both RNA and whole exome DNA genome sequencing from ANAVEX(R)2-73-treated patients utilizing Illumina HiSeq 2500 Next Generation Sequencing (NGS) technology. The analysis of this data has characterized several genomic alterations in well-characterized targets that have the potential to be used as biomarkers, which the Company plans to use to identify optimal patients in forthcoming clinical trials. This novel, precision-medicine approach will enable enriched clinical trial populations, more robust regulatory submissions and better characterized clinical trial designs. Full details of the genomic sequencing analysis have been submitted for presentation at an upcoming scientific meeting.


The strategic decision to incorporate these finding into all 3 trials seems to me to be right one and eludes to the idea that valid signals was indeed found strong enough to warrant not kicking off the trials in 2017.
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