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Re: BIOChecker4 post# 138128

Friday, 01/19/2018 1:34:37 PM

Friday, January 19, 2018 1:34:37 PM

Post# of 461432

as an investor in biotech who has been burned a few times because I drank the Kool-Aid and denied what in hindsight seemed obvious



Most of us have had our share of BT Kool Aide. We get that. We also get that the absence of new information/data for long periods is a symptom of something. We may have rationalized to say, that's b/c he was bitten once. We can accept that for a while, but not indefinitely. In my case the fact that many serious/talented people have written/published thoughts and papers which advocate for the science is important. The whole M/S-WSU/TA cycle mystery is continuing. historical MS/AD/PD RETT clinical data, and much more. We have not seen ANY contradictory serious technical paper. True, we have the continuous always negative, never stop axxholes who would be better off 6 ft under, but that's just life. Blah, blah , blah it goes for negative rationalization which we are all capable of.

Comst the point when we need to suck it up and go get some more facts about the science. The Rett trial is by far the best current opportunity(that we know of). To me RETT is a make or break b/c it is about the whole AVXL platform thesis/claim to restore/regen. Anyone who says it is just another trial does not get it. We are not the same crowd who continued to support FDA/BP repeated Ama-plaque failures for 20 yrs. The best the parasites can come up with is the AUS numbers are not big enough, even though there is zero evidence of ANY AD serious trial where pts ever walked away. Getting Rett trial done does two things, it validates the R&R thesis and provides new factual clinical information.

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