Anavex Life Sciences Corp (AVXL)

[sokol]

In the Just Paste it summary about AVXL someone posted the other day it said this: "....at higher doses, it acts as an antagonist on sodium and calcium channels. This mixed pharmacodynamic profilesuggests that ANAVEX 2-73 may also be an effective anti-amnesic, anti-depressant and neuroprotective drug [1] [2] [3] . Sigma-1 receptorsfunctionally downregulate certain proteins that play a major role in various pathophysiological conditions including depression, anxiety,epilepsy and brain injury following ischaemic stroke; it has been shown that activating the sigma-1 receptor with agonists can potentiallyreduce the impact of tau dysfunction....."

Funny, when I read that it acted on sodium and calcium channels I had the thought that AVXL may control blood pressure, which I think some postulate contributes to AD and cognitive decline. However, I am no expert either.