Anavex Life Sciences Corp (AVXL)

[XenaLives]

We are talking about a P2a here, not "most trials" - many P2a's are "unblinded and uncontrolled". The purpose of the P2a was to gather information about dosage and response levels. That is what happened.

Your entire post is one big red herring.

Why are most trials blinded and placebo controlled? Is it a good idea to put so many funding eggs into a Phase 2/3 basket based on results from a trial that was susceptible to significant bias because it was unblinded and uncontrolled? How many different doses will the next trial have with a sample size of only 200? What if the sample size, due to multiple doses, is too small for statistical significance?