Avid Bioservices Inc (CDMO)

[drragmop]

The reason the increase in pro-time and APPT was "expected" is that activated platelets display PS on their exteriors.

"Other studies looking at platelet activation showed that circulating unactivated platelets had low levels of phosphatidylserine on the outer leaflet of their membranes[footnote moitted]. However, when platelets were activated, the amount of phosphatidylserine on the outer leaflets increased dramatically from {approx} 2% of the phospholipid content to as much as 12%."

http://atvb.ahajournals.org/cgi/content/full/22/9/1381