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Thursday, 01/04/2018 12:33:12 PM

Thursday, January 04, 2018 12:33:12 PM

Post# of 16885
Mother Jones article....the journalist chronicles his addiction & exemplifies the reason most addicts need a partial agonist instead of an antagonist like Vivitrol.. …it's not about the high .. It's about not being sick.. also interesting is this journalist's odyssey through the US & EU treatment landscape.. Granted he notes he is in the 1% who have insurance & connections to get MAT.. his goal ultimately get off all drugs.. probuphine, if approved in EU, will significantly help addicts like him taper down, even if they may require additional oral rescue meds at some point (as he did when his MD told him to take another piece of buprenorphine film)…
http://www.motherjones.com/politics/2018/01/i-was-a-successful-journalist-when-a-doctor-first-handed-me-opioids/

also of interest is the 2nd article about Braeburn's injectable vs Indivior.. I didn't know Indivior's injectable requires refrigeration while Braeburn's does not.. we will see…

"Unlike Sublocade, which requires refrigeration, CAM2038 can be stored at room temperature. The product is delivered through a technology called FluidCrystal. It is ready for use in prefilled syringes with safety devices in doses of 8 mg to 32 mg for once-weekly administration and 64 mg to 160 mg for once-monthly injections." … while the article touts the flexibility of the injectables over the 6 month implant… the reviewers do not account for the psychological limitations of recovering addicts who are tethered to weekly or monthly doctor's visits (although better than the daily methadone grind)… the real world advantage of the 6 month implant is a big deal in getting back to a normal life…IMHO

https://www.medscape.com/viewarticle/890463
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