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Wednesday, 12/20/2017 3:22:00 PM

Wednesday, December 20, 2017 3:22:00 PM

Post# of 465236
I respectfully differ from those who feel that AVXL shareholders will have their greatest victory if and when the drug proves successful in treating any of the indications being set up for trials: Rett, PD, AD, MS, or others.

I propose that after trials are completed, if approval is obtained, that is when the share price will see its largest/fastest increase.

But, in truth, of the shareholders, who hold now, patiently, before the drug has been approved, and, who have taken on the risk and believed that the sacrifice was worth it based on preclinical data, published papers, early phase results, and who bore the silence of management - working behind the scenes to develop ongoing strategies, I say:

This is our finest hour.

Giving the blood, sweat, and tears, (and money) to help this aspiring company with scant resources and a novel approach wage the uphill battle of taking on an entrenched, antiquated, completely failed approach to battling CNS diseases and redefining the landscape for sufferers and sparing those yet to suffer; taking the full risk (cynics say fool risk), without being certain of the outcome...

When the able sacrifice to help the less able...

When humanity and the human condition mean more than the shekels made from horse trading...

When it would be easier to trade impatiently and think only of the short term profits, those who make the choice to unravel the cause of disease, end the turmoil, ease the pain and suffering of others, who, but for the Grace of God will be us some day, who aim to fulfill a prophecy never before written: that there can be hope for eradicating CNS devastation, and who have belief enough in this prophecy to risk affordable losses...

It will be said, that, because they knew not for certain...

This was their finest hour.

The share price is low, which means those with tenacity are at their highest degree of faith. Tests don’t come any harder than this - which is exactly what tests of the spirit are.

The rewards are there for those who have the strength to endure the test.
Even if the drug fails...
Even if the risks are great...
Even if opportunity costs exist and better returns on investment could be had elsewhere...

Because some took the risk to make their brethren healthier for much longer, and lessen the burden on caregivers, and to give Michael J Fox a second chance to be Michael J Fox once more, and to enable little girls with woes which fit no crime to grow up with a chance to encounter normalcy in their lives, and to make our mentally ravaged, withdrawn, elders more Ern-like (let’s not take out the garbage...:)
In fact, if WE can take the “garbage” out of the “Erns”, they can be themselves again...)

We will still be better off as a whole.

Put down your financial incentives and fight a war of valor against these marauding illnesses with your muscle, guts, glory, and determination.

This gathering storm mentality affecting our share price will test us.
Don’t wait until the trials are over to claim courage and stoic honor - we don’t have that luxury. Waiting until a Treaty has been signed to enlist is cowardice. Fight now, while the chips are down and the breaks are against us.

This is our finest hour.

“V”
Sir Winston Churchill

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