Saturday, December 09, 2017 11:05:18 AM
https://www.ted.com/talks/jeff_iliff_one_more_reason_to_get_a_good_night_s_sleep
Check the last three minutes of this Ted Talk, where the crucial role of sleep to clear beta-amyloid wastes is explained, preventing Alzheimer’s.
The fact that all of those Alzheimer’s patients with sleep problems in the Australian study got sound sleep while being dosed with Anavex 2-73 may, in the end, prove to be the most significant outcome.
As the presenter in the Ted Talk above mentioned, before many experience outright Alzheimer’s symptoms, sleep becomes ever more difficult and inadequate. Loss of sleep duration and quality is quite frequently the first indication of ensuing Alzheimer’s, as beta-amyloid wastes begin to accumulate from the loss of sleep.
So, what happens if Anavex 2-73 can be given prodromally, before outright symptoms appear? It is not unreasonable to envision (yet to be proved, of course) the following.
Anavex 2-73 proves itself and gets FDA approval as the new standard of care Alzheimer’s treatment. Several million American’s begin taking it in a year or two after approval. One of the first good outcomes is that sleep becomes normal and deep. Instead of getting up at night and fitfully wandering around and causing trouble, a major problem with Alzheimer’s patients, they all now sleep well.
It doesn’t take much of a brain to then think that, perhaps, it would be good to prescribe Anavex 2-73 to people who don’t yet have a full set of symptoms, just a few first hints of ensuing Alzheimer’s; forgot where the car keys were left, forgot why the person walked into the other rooms, and — no longer sleeping so well. Here, the general practitioner says, “Try a bit of this, Anavex 2-73. It should help you sleep better. Let’s see what happens.”
And, so it does. After a year or two of this, it is discovered that no one who was prescribed Anavex 2-73 just for good sleep went on to Alzheimer’s. Instead, their cognitive skills remained normal, with no ensuing dementia. Profound treatment success.
Profound benefits, too, to Anavex Life Sciences Corp, and to those of us who held our AVXL shares through those several years of little activity.
Here is another Ted Talk on the importance of sleep for health:
https://www.ted.com/talks/dan_gartenberg_the_brain_benefits_of_deep_sleep_and_how_to_get_more_of_it?utm_source=newsletter_weekly_2017-12-09&utm_campaign=newsletter_weekly&utm_medium=email&utm_content=talk_of_the_week_image#t-5139
[This author advises that his postings should not be used to prompt any AVXL buy or sell decision. Anavex Life Sciences Corp is presently a small, no-revenues, no-product start up pharmaceutical. It may have a great future, as its science is unique and effective. But, of course, never put at risk any non-discretionary funds.]
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