Anavex Life Sciences Corp (AVXL)

[falconer66a]

A News Headline Would Be a Big Kickoff

What might be the results of a New York Times headline in the fashion of:

"New Drug Likely To Get FDA Approval: Fixes Alxheimer's"

--- with accurate text and graphics accurately telling the Anavex story.

Things going to be very different when Anavex is in public discussion. Won't take much to prompt such an article. First inkling of efficacy from the Rett or Parkinson's trials would do it. A bit later, several months into the big Phase 3 Alzheimer's trial, this time at optimized doses with well-matched, treatable participants, word starts to spread that a bunch of people are no longer experiencing cognition decline; a few are actually thinking almost normally again. And everyone is now sleeping soundly.

That trial is supposed to be double blind; but there can be no blinding of enduring cognition stabilization, or better, cognition improvement.

It could be very difficult to try to maintain blindness in both arms. Placebo? No problem. Experimental (optimized Anavex 2-73) arm? Will get harder and harder as the trial progresses. Hard to disguise improved cognition, improved sleep habits, etc. Family members will notice (and rejoice).