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Re: kld2 post# 128558

Saturday, 11/04/2017 8:51:06 PM

Saturday, November 04, 2017 8:51:06 PM

Post# of 459598
No. And neither does Amgen, Novartis, Banner, Biogen and others.

“If we determine that our BACE1 inhibitor can prevent or delay the onset of symptoms in healthy yet high-risk populations, this would represent a tremendous breakthrough for those that may face this debilitating disease.”

frol, you mentioned in a previous post that it looked like the super-responders were mildly impaired. Don't you see that as potentially suspect? Why only them? When screening and assessing such patients, the diagnostic accuracy of the MMSE for detecting these individuals with baseline MCI is questionable.

In fact Anavex selected MMSE>20 as "early", while it sounds like the companies above may target "healthy", MMSE>24 as early. BP is suspect. Anavex is not.

IMHO
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