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Friday, November 03, 2017 12:32:57 PM
TSOI has several patents moving along re: Pterostilbene .
A lot of things goin on w/ ptero . and studies are showing ptero is ...a good read . from the beginning for all that want to catch up :
Cancer chemopreventive and antioxidant activities of pterostilbene, a naturally occurring analogue of resveratrol.
https://www.ncbi.nlm.nih.gov/pubmed/12033810
Dietary intake of pterostilbene, a constituent of blueberries, inhibits the beta-catenin/p65 downstream signaling pathway and colon carcinogenesis in rats.
Our data with pterostilbene in suppressing colon tumorigenesis, cell proliferation as well as key inflammatory markers in vivo and in vitro suggest the potential use of pterostilbene for colon cancer prevention.
https://www.ncbi.nlm.nih.gov/pubmed/20061362
Pterostilbene is more potent than resveratrol in preventing azoxymethane (AOM)-induced colon tumorigenesis via activation of the NF-E2-related factor 2 (Nrf2)-mediated antioxidant signaling pathway.
https://www.ncbi.nlm.nih.gov/pubmed/21355597
Pterostilbene Decreases the Antioxidant Defenses of Aggressive Cancer Cells In Vivo: A Physiological Glucocorticoids- and Nrf2-Dependent Mechanism.
CONCLUSIONS:
Pter downregulates glucocorticoid production, thus decreasing the glucocorticoid receptor and Nrf2-dependent signaling/transcription and the antioxidant protection of melanoma and pancreatic cancer cells.
https://www.ncbi.nlm.nih.gov/pubmed/26651028
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