Anavex Life Sciences Corp (AVXL)

[Amatuer17]

Very good find - could lead to a change in direction of thinking as it came from very reputable research inst.

This puts A2-73 ahead of all other drugs - even though it is still in P2 phase (yet to start)

Not sure how this impacts A2-73 visibility

Some interesting paras

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Cohen added that because the brain's nerve cells rely almost entirely on mitochondria-derived energy, failure of mitochondrial function, while seen throughout the body, might be particularly detrimental in the brain.

The study's results link to findings from other studies that decreasing energy-related molecules (and specifically NAD) are features of normal aging by suggesting that abnormalities in processes involving these molecules may also be a factor in neurodegenerative diseases like LOAD.

. Whether modulating these compounds could slow the aging process and prevent or delay the onset of LOAD is unknown.

...

"In fact, metabolic changes like diminished glucose uptake and insulin/IGF-1 resistance may underlie the association between various disorders of aging, such as type 2 diabetes and AD."

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